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Furthermore, Chapter B.42 should be added to Annex V in order to make available a refined method on subchronic oral toxicity.

The methods for subchronic oral toxicity in Chapters B.1, B.4, B.5, B.31 and B.35 should be revised accordingly. It is appropriate to amend that Annex in order to obtain a reduction to a minimum of the number of animals used for experimental purposes, in accordance with Council Directive 86/609/EEC of 24 November 1986 on the approximation of laws, regulations and administrative provisions of the Member States regarding the protection of animals used for experimental and other scientific purposes ( 2). The labelling of substances containing 1,3-butadiene should be changed in order to reflect that that substance will be classified as a mutagen by the present Directive.Īnnex V to Directive 67/548/EEC lays down the methods for the determination of the physicochemical properties, toxicity and ecotoxicity of substances and preparations.

Accordingly it is also necessary to delete entries for certain substances and to split some entries because the classification no longer applies to all the substances under those entries. That list needs to be updated to include further notified new substances and further existing substances as well adapting the existing entries to technical progress such as setting environmental concentration limits for certain substances. Having regard to Council Directive 67/548/EEC of 27 June 1967 on the approximation of the laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances ( 1), and in particular Article 28 thereof,Īnnex I to Directive 67/548/EEC contains a list of dangerous substances, together with particulars of the classification and labelling of each substance.

Having regard to the Treaty establishing the European Community, THE COMMISSION OF THE EUROPEAN COMMUNITIES, (ES, DA, DE, EL, EN, FR, IT, NL, PT, FI, SV)Īdapting to technical progress for the 29th time Council Directive 67/548/EEC on the approximation of the laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances Corrigendum to Commission Directive 2004/73/EC of 29 April 2004 adapting to technical progress for the 29th time Council Directive 67/548/EEC on the approximation of the laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances (Official Journal of the European Union L 152 of 30 April 2004)